Ming Dynasty Surgeons Used Poison to Numb Pain, Ancient Tools Reveal

By: | June 12th, 2026

A pair of surgical scissors from the Ming Dynasty tomb of physician Xia Quan (Image courtesy: Ling et al., Antiquity, 2026)

A Remarkable Medical Discovery

Modern anesthesia is often viewed as a relatively recent medical breakthrough, but new evidence suggests that physicians in China managed surgical pain with sophisticated techniques centuries ago. Researchers have discovered traces of a toxic plant compound on surgical instruments from the Ming Dynasty, providing rare physical evidence of ancient anesthetic practices.

Clues Hidden on Ancient Surgical Tools

The discovery centers on a set of iron surgical scissors and tweezers that belonged to Xia Quan, a physician who lived during the early Ming Dynasty between 1348 and 1411. Archaeologists recovered these instruments from his tomb in Jiangyin County, China, decades ago. Recently, scientists used advanced analytical techniques to examine microscopic residues preserved on the tools.

Their investigation detected aconitine, a potent toxin found in plants of the Aconitum genus, commonly known as wolfsbane or monkshood. Although the raw plant contains dangerous toxins, traditional Chinese healers developed methods to process it and reduce its harmful effects. They then used the substance for its medicinal and pain-relieving properties.

Evidence of Ancient Pain Management

Historical texts have described the use of herbal anesthetics in China for centuries, but researchers rarely find direct physical evidence. The newly identified chemical traces strongly support the idea that physicians prepared specialized plant-based mixtures for surgical procedures.

Researchers believe surgeons applied processed aconitine directly to a patient’s skin before surgery to numb the treatment area and reduce pain. By carefully handling and refining such a dangerous substance, these physicians demonstrated a sophisticated understanding of medicinal plants and human physiology.

Rethinking Medical History

The findings challenge the notion that effective anesthesia emerged only in the modern era. Instead, they highlight the ingenuity of Ming Dynasty physicians, who developed practical approaches to pain management long before doctors introduced ether and other modern anesthetics.

This discovery not only sheds light on ancient Chinese medical practices but also reveals how early physicians combined observation, experimentation, and herbal knowledge to make surgical procedures safer and more tolerable for their patients.

Nidhi Goyal

Nidhi is a gold medalist Post Graduate in Atmospheric and Oceanic Sciences.

More articles from Industry Tap...